Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504796 | 0.95 | FFAR1 (0.35) | FFAR1PPARGPPARA | |
| SCHEMBL504050 | 0.94 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL503726 | 0.92 | PPARG (0.35) | PPARG | |
| SCHEMBL504368 | 0.91 | AGTR1 (0.34) | — | |
| SCHEMBL503954 | 0.89 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL504049 | 0.88 | APLNR (0.34) | PPARGPPARA | |
| SCHEMBL504366 | 0.87 | ACHE (0.40) | — | |
| SCHEMBL504036 | 0.87 | ACHE (0.40) | — | |
| SCHEMBL504305 | 0.86 | ACHE (0.40) | — | |
| SCHEMBL504759 | 0.86 | APLNR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664226-B2 | Compound having 3-heteroarylpyrimidin-4-(3H)-one structure and pharmaceutical preparation containing same | KOWA COMPANY, LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| EP-2420501-A1 | NOVEL COMPOUND HAVING 3-HETEROARYLPYRIMIDIN-4-(3H)-ONE STRUCTURE AND PHARMACEUTICAL PREPARATION CONTAINING SAME | Kowa Company, Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |