Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965069 | 0.82 | CHEK1 (0.46) | POLBTRPV1MKNK1MKNK2KDM4E | |
| Hydrochloric Acid SCHEMBL7999913 | 0.81 | CHEK1 (0.45) | POLBTRPV1MKNK1MKNK2KDM4E | |
| SCHEMBL9368276 | 0.78 | LMNA (0.46) | LMNAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL6330297 | 0.78 | POLB (0.43) | LMNAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL3481165 | 0.75 | POLB (0.44) | LMNAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL11124116 | 0.74 | LMNA (0.46) | LMNAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL11448795 | 0.73 | ALDH1A1 (0.51) | LMNAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL8574831 | 0.72 | PARP10 (0.62) | POLBALDH1A1HSD17B10TRPV1MKNK1 | |
| SCHEMBL6331746 | 0.72 | MAPT (0.43) | LMNAPOLBALDH1A1TSHRKDM4E | |
| SCHEMBL2542278 | 0.72 | HTT (0.58) | POLBALDH1A1KDM4EHTTNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852888-B2 | Carboxylic acid derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1084100-B1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2004-07-14 | — | — | EP | disclosed |
| US-20030216467-A1 | Carboxylic acid derivatives | SYNGENTA CROP PROTECTION, INC. (FORMERLY KNOWN AS NOVARTIS CROP PROTECTION, INC.) | 2003-11-20 | — | — | US | disclosed |
| EP-1084100-A1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | Novartis AG (CH) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062866-A1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 1999-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216467-A1 | Carboxylic acid derivatives | CLIC1, CNPY3, HCFC1 | LMNA 533/4885POLB 4167/4885ALDH1A1 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.