Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196712 | 1.00 | TSHR (0.46) | TSHRCTSCCYP1A2EPHX1TRPA1 | |
| SCHEMBL6334251 | 1.00 | TSHR (0.46) | TSHRCTSCCYP1A2EPHX1TRPA1 | |
| SCHEMBL12704715 | 0.83 | MAOB (0.58) | CYP1A2MAOBPTGS1SLC6A2MAOA | |
| SCHEMBL30045268 | 0.80 | ESR1 (0.60) | CYP1A2SLC7A5SLC6A2TAAR1 | |
| SCHEMBL30420182 | 0.79 | PPARG (0.48) | TSHR | |
| SCHEMBL18703964 | 0.78 | SLC6A4 (0.48) | CTSCCYP1A2MAOBSLC6A2MAOA | |
| SCHEMBL3997283 | 0.78 | CTSC (0.44) | TSHRCTSCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2163440 | 0.78 | CTSC (0.44) | TSHRCTSCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4323888 | 0.78 | CTSC (0.44) | TSHRCTSCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11575105 | 0.78 | CTSC (0.44) | TSHRCTSCCYP1A2EPHX1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838581-B2 | Process for the preparation of enantiomerically pure 3-phenyl-3-hydroxypropylamine | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-01-04 | — | — | US | disclosed |
| US-20040110985-A1 | Process for the preparation of enantiomerically pure 3-phenyl-3-hydroxypropylamine | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110985-A1 | Process for the preparation of enantiomerically pure 3-phenyl-3-hydroxypropylamine | CYP2D6, ADH1A, TPH1 | TSHR 3383/4885CTSC 4411/4885CYP1A2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.