SCHEMBL6338656

SCHEMBL6338656

O=C(O)Cc1ccc(Oc2ccc(OCc3ccccc3)cc2)nc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACACB O00763 3/20 0.55
ACACA Q13085 3/20 0.55
FFAR1 O14842 5/20 0.54
FFAR4 Q5NUL3 3/20 0.54
OPRM1 P35372 2/20 0.51
OPRD1 P41143 2/20 0.51
OPRK1 P41145 2/20 0.51
ALOX5 P09917 2/20 0.50
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
MEN1 O00255 1/20 0.50
PABPC1 P11940 1/20 0.50
KMT2A Q03164 1/20 0.50
P4HTM Q9NXG6 1/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.48
MAOB P27338 1/20 0.48
PARP10 Q53GL7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6341556 0.90 ALOX5 (0.51) ACACBACACAFFAR1FFAR4OPRM1
SCHEMBL7452934 0.89 SRD5A2 (0.54) ACACBFFAR1OPRM1OPRD1OPRK1
SCHEMBL6341082 0.84 FFAR1 (0.68) FFAR1FFAR4ALOX5NR4A1NR4A2
SCHEMBL6349045 0.83 PPARD (0.49) ACACBACACAFFAR1FFAR4ALOX5
SCHEMBL6338798 0.83 FFAR4 (0.54) ACACBACACAFFAR1FFAR4
SCHEMBL1066614 0.82 FFAR1 (0.70) FFAR1FFAR4ALOX5NR4A1NR4A2
SCHEMBL6339254 0.82 NR4A2 (0.68) ACACBACACAOPRM1OPRD1OPRK1
SCHEMBL11816285 0.82 EGLN1 (0.49) OPRM1OPRD1OPRK1P4HTMPTGDR2
SCHEMBL1547117 0.81 LMNA (0.64) ACACBACACAOPRM1OPRD1OPRK1
SCHEMBL4222632 0.81 FFAR1 (0.68) FFAR1FFAR4ALOX5NR4A1NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 ACACB 1367/4885ACACA 1115/4885FFAR1 1564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.