Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GNG2 | P59768 | 1/20 | 0.34 |
| ▸ | GNB1 | P62873 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077118 | 0.91 | ALDH1A1 (0.45) | OPRL1ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL4079070 | 0.89 | ALDH1A1 (0.44) | OPRL1ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL6346659 | 0.80 | OPRL1 (0.42) | OPRL1ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL4076953 | 0.78 | ALDH1A1 (0.44) | OPRL1ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL4083571 | 0.78 | ALDH1A1 (0.46) | OPRL1ALDH1A1CASP1CASP7HSD17B10 | |
| SCHEMBL4081856 | 0.76 | TERT (0.36) | TERT | |
| SCHEMBL440491 | 0.69 | NR4A2 (0.74) | ALDH1A1CASP1CASP7HSD17B10NR4A2 | |
| SCHEMBL27906713 | 0.68 | ALDH1A1 (0.65) | ALDH1A1CASP1CASP7HSD17B10DOT1L | |
| SCHEMBL4077095 | 0.67 | TERT (0.63) | DOT1LTERT | |
| SCHEMBL4076941 | 0.67 | NCF1 (0.41) | OPRL1ALDH1A1CASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887873-B2 | Triazine derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2005-05-03 | — | — | US | claimed |