SCHEMBL6339149

SCHEMBL6339149

O=C(Cc1ccc(Oc2ccc(OCc3ccccc3)cc2)nc1)Nc1ccc(Cl)cc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.49
SAE1 Q9UBE0 1/20 0.49
UBA2 Q9UBT2 1/20 0.49
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
GAA P10253 1/20 0.48
PKM P14618 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
POLB P06746 1/20 0.45
G6PD P11413 1/20 0.45
PTGER1 P34995 1/20 0.44
ACACB O00763 2/20 0.44
ACACA Q13085 2/20 0.44
THRB P10828 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6340186 0.92 SAE1 (0.47) SAE1UBA2KDM4EALDH1A1GAA
SCHEMBL8037918 0.83 SERPINE1 (0.57) SERPINE1KDM4EALDH1A1GAAPKM
SCHEMBL6340616 0.83 MEN1 (0.54) KDM4EALDH1A1PKMMEN1KMT2A
SCHEMBL6339661 0.82 ALDH1A1 (0.53) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL6339038 0.81 CTSV (0.48) KDM4EALDH1A1PKMMEN1KMT2A
SCHEMBL6349289 0.79 ACACB (0.46) ALDH1A1PKMMEN1KMT2APOLB
SCHEMBL6348822 0.78 CTSV (0.48) KDM4EALDH1A1PKMMEN1KMT2A
SCHEMBL6346488 0.78 CTSV (0.46) KDM4EALDH1A1PKMMEN1KMT2A
SCHEMBL6338656 0.77 ACACB (0.55) MEN1KMT2AACACBACACA
SCHEMBL6338905 0.77 KDM4E (0.47) KDM4EALDH1A1MEN1KMT2AACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 SERPINE1 141/4885SAE1 1608/4885UBA2 3123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.