Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633370 | 0.88 | MAPT (0.48) | ALDH1A1MAPTHPGDSHMT2TP53 | |
| SCHEMBL6339434 | 0.87 | KMT2A (0.55) | ALDH1A1MAPTHPGDTP53HSD17B10 | |
| SCHEMBL9213788 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDSHMT2TP53 | |
| SCHEMBL9220907 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDSHMT2TP53 | |
| SCHEMBL9216519 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDSHMT2TP53 | |
| SCHEMBL6336301 | 0.80 | PPARA (0.46) | ALDH1A1MAPTTP53HSD17B10KDM4E | |
| SCHEMBL6210938 | 0.76 | TP53 (0.57) | ALDH1A1MAPTHPGDTP53HSD17B10 | |
| SCHEMBL6655241 | 0.75 | POLB (0.54) | ALDH1A1MAPTHPGDSHMT2TP53 | |
| SCHEMBL9218073 | 0.75 | MAPT (0.65) | ALDH1A1MAPTHPGDSHMT2TP53 | |
| SCHEMBL9213780 | 0.75 | MAPT (0.62) | ALDH1A1MAPTHPGDSHMT2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416798-A2 | THIAZOLO 4,5-b]PYRIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-12 | — | — | EP | claimed |
| US-20030083311-A1 | Thiazolo [4,5-b] pyridines as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-01 | — | — | US | claimed |
| WO-2003006470-A2 | THIAZOLO [4,5-b]PYRIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-23 | — | — | WO | claimed |
| US-6914068-B2 | Thiazolo[4,5-b]pyridines as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-05 | — | — | US | disclosed |
| EP-1416798-A2 | THIAZOLO 4,5-b]PYRIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-12 | — | — | EP | disclosed |
| US-20030083311-A1 | Thiazolo [4,5-b] pyridines as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-01 | — | — | US | disclosed |
| WO-2003006470-A2 | THIAZOLO [4,5-b]PYRIDINES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-23 | — | — | WO | disclosed |
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083311-A1 | Thiazolo [4,5-b] pyridines as fungicides | CBR1, CBR3, CNPY2 | ALDH1A1 485/4885MAPT 3901/4885HPGD 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.