Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218073 | 0.90 | MAPT (0.65) | MAPTALDH1A1HPGDSHMT2TP53 | |
| SCHEMBL9220907 | 0.83 | ALDH1A1 (0.70) | MAPTALDH1A1HPGDSHMT2TP53 | |
| SCHEMBL9215562 | 0.83 | MAPT (0.62) | MAPTALDH1A1HPGDSHMT2TP53 | |
| SCHEMBL2174930 | 0.78 | CYP2C9 (0.56) | MAPTALDH1A1TP53POLBCYP2C9 | |
| SCHEMBL615683 | 0.77 | MAPT (1.00) | MAPTALDH1A1HPGDSHMT2TP53 | |
| SCHEMBL9217493 | 0.75 | CYP1A2 (0.44) | MAPTALDH1A1HPGDPOLBTHRB | |
| SCHEMBL9216519 | 0.75 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDSHMT2TP53 | |
| SCHEMBL6340595 | 0.75 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDSHMT2TP53 | |
| SCHEMBL9272981 | 0.73 | CYP2C9 (0.43) | MAPTALDH1A1HPGDSHMT2CYP2C9 | |
| SCHEMBL13471437 | 0.71 | ALDH1A1 (0.71) | MAPTALDH1A1HPGDSHMT2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | disclosed |