Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6336981 | 0.88 | CYP1A2 (0.43) | ALDH1A1L3MBTL1MAPTNPSR1LMNA | |
| Hydrochloric Acid SCHEMBL6334170 | 0.84 | HTT (0.44) | ALDH1A1L3MBTL1TDP1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6330826 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6331163 | 0.77 | NQO1 (0.32) | — | |
| SCHEMBL10998289 | 0.73 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| Hydrochloric Acid SCHEMBL27552459 | 0.73 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1MAPTNPSR1LMNA | |
| Hydrochloric Acid SCHEMBL6337576 | 0.72 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| 1,2-Diethoxybenzene SCHEMBL578986 | 0.71 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| Hydrochloric Acid SCHEMBL6334274 | 0.71 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| 1,2-Diethoxybenzene SCHEMBL29428929 | 0.71 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPTNPSR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6870017-B2 | Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-03-22 | — | — | US | disclosed |
| CN-1174002-C | Transition metal compound, catalyst for polyaddition and method for preparing addition polymer | 住友化学工业株式会社 | 2004-11-03 | — | — | CN | disclosed |
| US-20030171212-A1 | Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-09-11 | — | — | US | disclosed |
| US-6548686-B2 | Coordination catalysts; suppresses heat generation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-04-15 | — | — | US | disclosed |
| US-20020013433-A1 | Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013433-A1 | Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer | ASH2L, ARL1, AS3MT | SLC6A2 4111/4885SLC6A3 3943/4885ALDH1A1 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.