Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | AGXT | P21549 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510845 | 0.89 | PTGS2 (0.46) | IDO1AGXTAPPHTTNPC1 | |
| SCHEMBL1456261 | 0.89 | PTGS2 (0.46) | IDO1AGXTAPPHTTNPC1 | |
| SCHEMBL9306727 | 0.81 | APP (0.40) | IDO1AGXTAPPHTTNPC1 | |
| SCHEMBL208838 | 0.80 | NQO1 (0.54) | NPC1POLBRAB9ASMN1; SMN2CA12 | |
| SCHEMBL9532692 | 0.80 | TAAR1 (0.52) | IDO1NPC1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL11324512 | 0.79 | ABCB1 (0.62) | APPNPC1RAB9A | |
| SCHEMBL10254222 | 0.79 | IDO1 (0.55) | IDO1AGXTAPPHTTMAOB | |
| SCHEMBL8853 | 0.79 | ALDH1A1 (0.46) | POLBCALM1 | |
| SCHEMBL2245598 | 0.79 | IDO1 (0.55) | IDO1AGXTAPPHTTNPC1 | |
| SCHEMBL2095384 | 0.79 | POLB (0.51) | NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 19086 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164998-A | Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof | 沈阳药科大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118164996-A | Sesquiterpene lactone scaberol C selenoether derivative, preparation method and application thereof | 沈阳药科大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118164997-A | Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof | 沈阳药科大学 | 2024-06-11 | — | — | CN | claimed |
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| US-20240124461-A1 | PROCESSES FOR THE PREPARATION OF ZANUBRUTINIB AND INTERMEDIATES THEREOF | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2024-04-18 | — | — | US | claimed |
| US-11932666-B2 | Polymerizable compound, compound, and method for producing boranophosphate oligomer | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2024-03-19 | — | — | US | claimed |
| EP-4282973-A2 | PROCESSES FOR THE PREPARATION OF PYRIMIDINYLCYCLOPENTANE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2023-11-29 | — | — | EP | claimed |
| EP-4259633-A1 | PROCESSES FOR THE PREPARATION OF ZANUBRUTINIB AND INTERMEDIATES THEREOF | Teva Pharmaceuticals International GmbH (CH) | 2023-10-18 | — | — | EP | claimed |
| WO-2023167545-A1 | POLYBENZIMIDAZOLE WITH PROTECTING GROUPS, PREPARATION METHOD FOR MEMBRANE USING THE SAME AND USE THEREOF | 한국화학연구원 | 2023-09-07 | — | — | WO | claimed |
| CN-116478165-A | Crystal form of compound, preparation and application thereof | 百济神州(苏州)生物科技有限公司 | 2023-07-25 | — | — | CN | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3998795-A | (Acyl-D-α-amino acid-gly-gly-tyr-ala)1 -somatostatin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-12-21 | — | — | US | claimed |
| US-3997517-A | PEPTIDE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-12-14 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
| US-3984417-A | Method of producing active amino acid esters | AJINOMOTO CO., INC. (JA) | 1976-10-05 | — | — | US | claimed |
| US-3978063-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-31 | — | — | US | claimed |
| US-3951951-A | Azetidinones | BEECHAM GROUP LIMITED (EN) | 1976-04-20 | — | — | US | claimed |
| US-3933783-A | Formation of peptide bonds in the presence of isonitriles | AJINOMOTO CO., INC. (JA) | 1976-01-20 | — | — | US | claimed |
| US-3933784-A | Des-(ser13)-srif and intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-20 | — | — | US | claimed |
| US-3931140-A | (H-gly-gly-tyr-ala)1 -somatostatin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-06 | — | — | US | claimed |