Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861366 | 0.83 | HRH3 (0.38) | NPC1RAB9AFFAR1ALDH1A1 | |
| SCHEMBL208838 | 0.81 | NQO1 (0.54) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL6341 | 0.81 | IDO1 (0.55) | APPNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL14341660 | 0.81 | APP (0.47) | APPNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL9249948 | 0.79 | LMNA (0.50) | SMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL2090023 | 0.79 | KDM4E (0.49) | SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL5545390 | 0.76 | LMNA (0.58) | APPRAB9ASMN1; SMN2MAOBFFAR1 | |
| SCHEMBL3589633 | 0.76 | NQO1 (0.50) | APPMAOBMAPTMMP2MMP3 | |
| SCHEMBL6158474 | 0.76 | IDO1 (0.64) | MAOBIDO1AGXT | |
| SCHEMBL28307415 | 0.75 | MMP2 (0.40) | APPFFAR1MAPTALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371210-A | Reacting alpha anomer enriched 2-deoxy-2,2-difluorocarbo-hydrate with nucleobase | ELI LILLY AND COMPANY (US) | 1994-12-06 | — | — | US | disclosed |