SCHEMBL634331

SCHEMBL634331

CCC(=O)c1ccccc1Br

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
F2R P25116 2/20 0.53
ALDH1A1 P00352 8/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HPGD P15428 3/20 0.50
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 3/20 0.45
HTT P42858 2/20 0.45
LMNA P02545 1/20 0.45
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29573770 1.00 KMT2A (0.53) KMT2AF2RALDH1A1SMN1; SMN2HPGD
SCHEMBL7757008 0.84 KMT2A (0.44) KMT2AF2RALDH1A1SMN1; SMN2HPGD
SCHEMBL13990159 0.84 L3MBTL1 (0.52) KMT2AALDH1A1SMN1; SMN2HSD17B10L3MBTL1
SCHEMBL27596818 0.83 F2R (0.46) KMT2AF2RALDH1A1SMN1; SMN2HPGD
SCHEMBL29573179 0.83 F2R (0.51) KMT2AF2RALDH1A1SMN1; SMN2HPGD
SCHEMBL2336667 0.83 F2R (0.51) KMT2AF2RALDH1A1SMN1; SMN2HPGD
SCHEMBL30089542 0.82 ALDH1A1 (0.53) KMT2AALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL15979732 0.82 ALDH1A1 (0.53) KMT2AALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL28053559 0.82 ALDH1A1 (0.53) KMT2AALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL27673463 0.82 F2R (0.45) KMT2AF2RALDH1A1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 673 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113178602-A Preparation of ZIF-8/polyether-ether-ketone and ZIF-8@ GO/polyether-ether-ketone anion composite membrane 长春工业大学 2021-07-27 CN claimed
CN-110305048-A One kind preparing α-sulfuryl ketone compounds synthetic method by α, α-two bromo ketone one kettle way 温州大学 2019-10-08 CN claimed
CN-110092724-A A kind of preparation method of N, N- dimethyl-1-naphthylamine class compound 湖南大学 2019-08-06 CN claimed
CN-106831784-B The method of one pot of tandem reaction synthesis tryptamines ketone alkaloid 河南师范大学 2019-07-19 CN claimed
CN-106083686-B The method of alpha-brominated acetophenone oxime ether synthesis 2,4- diaryl pyrrole class compound 苏州大学 2019-01-22 CN claimed
CN-105924325-B A kind of preparation method of 6,6,12,12- tetramethyl -6,12- dihydro indeno [1,2-b] fluorenes 东阳市天齐知识产权运营有限公司 2018-11-30 CN claimed
CN-106442829-A Method of simultaneously detecting contents of fatty acid and active matter in fatty acyl neutral amino acid surfactant 广州天赐高新材料股份有限公司 2017-02-22 CN claimed
CN-106083810-A A kind of preparation method of polysubstituted thiochromanone derivant 青岛科技大学 2016-11-09 CN claimed
CN-106008137-A Preparation method of 6,6,12,12-tetramethyl-6,12-dihydroindeno[1,2-b] fluorene 李金铃 2016-10-12 CN claimed
CN-105924325-A Preparation method of 6,6,12,12-tetramethyl-6,12-dihydro indeno [1,2-b] fluorene 李金铃 2016-09-07 CN claimed
CN-103755732-B Adjacent phenyl chalcone compounds and its preparation method and application 中山大学 2016-06-08 CN claimed
CN-104803816-A Preparation method of carboxylic ester UNIV EAST CHINA NORMAL 2015-07-29 CN claimed
CN-104508116-A Pesticidal flavobacterium strains and bioactive compositions, metabolites and uses MARRONE BIO INNOVATIONS INC 2015-04-08 CN claimed
CN-103755732-A O-phenyl chalcone compound as well as preparation method and application thereof UNIV SUN YAT SEN 2014-04-30 CN claimed
CN-101500996-B (3-amino-1,2,3,4-tetrahydro-9h-carbazol-9-yl)-acetic acid derivatives ACTELION PHARMACEUTICALS LTD 2012-07-04 CN claimed
US-20060153929-A1 Use of solid phase synthesis to modify and to assemble nanoparticles INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2006-07-13 US claimed
JP-62238233-A None JP disclosed
US-12583882-B2 Equatorially modified polymer linked multimers of guansine-3′, 5′-cyclic monophosphates MIRECA MEDICINES GMBH (DE) 2026-03-24 US disclosed
EP-0006627-A2 Radiation-sensitive mixture and process for producing relief images HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-09 EP disclosed
US-3964896-A Oxadiazole benzoic acid derivatives as herbicides UNIROYAL, INC. (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583882-B2 Equatorially modified polymer linked multimers of guansine-3′, 5′-cyclic monophosphates PDE7A, PRKG1, NT5C3B KMT2A 3091/4885F2R 2152/4885ALDH1A1 2473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.