Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6345159 | 0.91 | ITGB1 (0.61) | ITGB3ITGB1ITGA4MAPTNPC1 | |
| SCHEMBL6786428 | 0.84 | ITGB3 (0.67) | LMNAHPGDITGB3ITGA2BTSHR | |
| SCHEMBL19501811 | 0.78 | LMNA (0.81) | LMNAHPGDTSHRMAPTGAA | |
| SCHEMBL6344910 | 0.77 | ITGB1 (0.57) | ITGB1ITGA4 | |
| SCHEMBL6353720 | 0.77 | POLB (0.58) | LMNAHPGDITGB3ITGA2BITGB1 | |
| SCHEMBL6794878 | 0.77 | ITGB1 (0.62) | ITGB3ITGA2BITGB1ITGA4MAPT | |
| SCHEMBL6346596 | 0.75 | ITGB1 (0.54) | ITGB3ITGA2BITGB1ITGA4MAPT | |
| SCHEMBL13645741 | 0.74 | TSHR (0.60) | LMNAHPGDTSHRMAPTKMT2A | |
| SCHEMBL10931873 | 0.74 | POLB (0.63) | LMNAHPGDTSHRMAPTGAA | |
| SCHEMBL19501437 | 0.73 | MAPT (0.79) | HPGDTSHRMAPTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | claimed |