Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343533 | 0.90 | MAPT (0.48) | ITGB1ITGA4ANPEP | |
| SCHEMBL6345159 | 0.87 | ITGB1 (0.61) | ITGB1ITGA4 | |
| SCHEMBL6794878 | 0.84 | ITGB1 (0.62) | ITGB1ITGA4 | |
| SCHEMBL6343091 | 0.83 | ITGB1 (0.58) | ITGB1ITGA4 | |
| SCHEMBL7466957 | 0.82 | ITGB1 (0.66) | ITGB1ITGA4 | |
| SCHEMBL6343632 | 0.81 | ITGB1 (0.60) | ITGB1ITGA4 | |
| SCHEMBL6344106 | 0.81 | ITGB1 (0.47) | ITGB1ITGA4 | |
| SCHEMBL6344990 | 0.80 | RAB9A (0.54) | ITGB1ITGA4 | |
| SCHEMBL6344005 | 0.77 | LMNA (0.52) | ITGB1ITGA4 | |
| SCHEMBL6340867 | 0.76 | ITGB1 (0.58) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | claimed |
| US-20040053907-A1 | Cell adhesion inhibitors | BIOGEN, INC. A MASSACHUSETTS CORPORATION. | 2004-03-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053907-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | ITGB1 11/4885ITGA4 37/4885ANPEP 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.