Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321988 | 0.88 | PDPK1 (0.66) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8664436 | 0.88 | PDPK1 (0.66) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11748233 | 0.85 | HTT (0.60) | HTTALDH1A1KMT2AMEN1EPHX1 | |
| SCHEMBL2115700 | 0.84 | HTT (0.63) | HTTALDH1A1KMT2AMEN1EPHX1 | |
| SCHEMBL18539244 | 0.81 | LMNA (0.55) | HTTALDH1A1KMT2AMEN1EPHX1 | |
| SCHEMBL61094 | 0.81 | PDPK1 (0.79) | HTTALDH1A1KMT2AMEN1EPHX1 | |
| SCHEMBL61095 | 0.81 | PDPK1 (0.79) | HTTALDH1A1KMT2AMEN1EPHX1 | |
| SCHEMBL5270795 | 0.81 | LMNA (0.55) | HTTALDH1A1KMT2AMEN1EPHX1 | |
| SCHEMBL61380 | 0.81 | PDPK1 (0.79) | HTTALDH1A1KMT2AMEN1EPHX1 | |
| SCHEMBL15295177 | 0.81 | LMNA (0.55) | HTTALDH1A1KMT2AMEN1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030215531-A1 | Compositions and methods of use for extracts of Rutaceae plants | STOGNIEW MARTIN (US) | 2003-11-20 | — | — | US | claimed |
| US-20020061339-A1 | Compositions and methods for use of extracts of rutaceae plants | NPI, LLC. | 2002-05-23 | — | — | US | claimed |
| WO-2002026244-A2 | COMPOSITIONS AND METHODS OF USE FOR EXTRACTS OF RUTACEAE PLANTS | NEXT PHARMACEUTICALS, INC. (US) | 2002-04-04 | — | — | WO | claimed |
| EP-3943500-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | Agilent Technologies, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| US-6844368-B1 | Compounds useful in pain management | ASTRAZENECA CANADA INC. (CA) | 2005-01-18 | — | — | US | disclosed |
| US-20030215531-A1 | Compositions and methods of use for extracts of Rutaceae plants | STOGNIEW MARTIN (US) | 2003-11-20 | — | — | US | disclosed |
| US-20020061339-A1 | Compositions and methods for use of extracts of rutaceae plants | NPI, LLC. | 2002-05-23 | — | — | US | disclosed |
| WO-2002026244-A2 | COMPOSITIONS AND METHODS OF USE FOR EXTRACTS OF RUTACEAE PLANTS | NEXT PHARMACEUTICALS, INC. (US) | 2002-04-04 | — | — | WO | disclosed |
| JP-2000007624-A | PRODUCTION OF OPTICALLY ACTIVE 2-AMINO-SUBSTITUTED TETRALIN | SUMIKA FINE CHEMICALS CO LTD | 2000-01-11 | — | — | JP | disclosed |
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |
| US-4500545-A | HYPOTENSIVE, ANTISECRETORY AGENTS, AND DOPAMINE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| US-4448990-A | Hydroxyaminotetralincarboxamides | ELI LILLY AND COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| US-4062856-A | ANIMAL GROWTH REGULATOR, HERBICIDE | AMERICAN CYANAMID CO. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4005140-A | ANIMAL GROWTH REGULATORS, HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-3953506-A | ANIMAL GROWTH REGULATORS, HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1976-04-27 | — | — | US | disclosed |