Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13543527 | 0.84 | SMN1; SMN2 (0.53) | CCR3CYP11B1CYP11B2SMN1; SMN2HTT | |
| SCHEMBL3523976 | 0.84 | SMN1; SMN2 (0.53) | CCR3CYP11B1CYP11B2SMN1; SMN2HTT | |
| SCHEMBL1573878 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAPKMSLC6A2 | |
| SCHEMBL6017062 | 0.74 | CYP11B2 (0.43) | CYP11B2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6344442 | 0.71 | CCR3 (0.54) | CCR3CYP11B1CYP11B2SLC6A2SLC6A4 | |
| SCHEMBL2711944 | 0.68 | CCR3 (0.48) | CCR3SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL31587253 | 0.67 | ALDH1A1 (0.46) | CCR3SMN1; SMN2HTTMAPK1TBXA2R | |
| SCHEMBL10268288 | 0.66 | HTR3E (0.45) | TBXA2RCHRM1 | |
| SCHEMBL16128124 | 0.66 | OPRM1 (0.45) | CCR3CYP11B1CYP11B2SMN1; SMN2HTT | |
| SCHEMBL3527117 | 0.65 | LMNA (0.47) | SMN1; SMN2HTTMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648888-A1 | N-(HETEROBICYCLOALKANES)-SUBSTITUTED INDOLES OR HETERODERIVATIVES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2006-04-26 | — | — | EP | disclosed |
| US-20050014782-A1 | Novel n-(heterobicycloalkanes)-substituted indoles-or heteroderivatives thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
| WO-2005005425-A1 | N-(HETEROBICYCLOALKANES)-SUBTITUTED INDOLES- OR HETERODERIVATIVES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | WO | disclosed |
| EP-1496058-A1 | Novel N-(heterobicycloalkanes)-substituted Indoles or heteroderivatives thereof | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014782-A1 | Novel n-(heterobicycloalkanes)-substituted indoles-or heteroderivatives thereof | CCR3, CCR1, CCRL2 | CCR3 1/4885CYP11B1 493/4885CYP11B2 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.