Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6354375 | 0.97 | ALDH1A1 (0.43) | ALDH1A1SLC6A9CYP3A4MEN1KMT2A | |
| SCHEMBL7092690 | 0.94 | SLC6A9 (0.45) | ALDH1A1SLC6A9CYP3A4MEN1KMT2A | |
| SCHEMBL6347185 | 0.91 | SLC6A9 (0.45) | ALDH1A1SLC6A9CYP3A4MEN1KMT2A | |
| SCHEMBL6344428 | 0.87 | ALDH1A1 (0.42) | ALDH1A1SLC6A9CYP3A4MEN1KMT2A | |
| SCHEMBL6357878 | 0.87 | ALDH1A1 (0.44) | ALDH1A1SLC6A9CYP3A4MEN1KMT2A | |
| SCHEMBL6342761 | 0.86 | ALDH1A1 (0.42) | ALDH1A1SLC6A9MEN1KMT2AHTT | |
| SCHEMBL6345481 | 0.84 | ALDH1A1 (0.42) | ALDH1A1SLC6A9CYP3A4MEN1KMT2A | |
| SCHEMBL6346463 | 0.83 | ALDH1A1 (0.45) | ALDH1A1SLC6A9CYP3A4MEN1KMT2A | |
| SCHEMBL6347843 | 0.83 | SLC6A4 (0.43) | ALDH1A1 | |
| SCHEMBL6354373 | 0.83 | ALDH1A1 (0.43) | ALDH1A1SLC6A9CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900353-B2 | Cyclopentyl sulfonamide derivatives | ELI LILLY AND COMPANY (US) | 2005-05-31 | — | — | US | claimed |
| EP-1334087-A1 | CYCLOALKYLFLUOROSULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-08-13 | — | — | EP | claimed |
| WO-2002032858-A1 | CYCLOALKYLFLUOROSULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-04-25 | — | — | WO | claimed |
| US-20040067984-A1 | Cyclopentyl sulfonamide derivatives | CANTRELL BUDDY EUGENE (US) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067984-A1 | Cyclopentyl sulfonamide derivatives | GRIN2A, GRIN1, GRIK5 | ALDH1A1 642/4885SLC6A9 217/4885CYP3A4 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.