Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6347185 | 0.97 | SLC6A9 (0.45) | SLC6A9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6344448 | 0.94 | ALDH1A1 (0.42) | SLC6A9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6354375 | 0.91 | ALDH1A1 (0.43) | SLC6A9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6357878 | 0.88 | ALDH1A1 (0.44) | SLC6A9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6349725 | 0.87 | SLC6A9 (0.44) | SLC6A9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6346463 | 0.85 | ALDH1A1 (0.45) | SLC6A9CYP3A4MEN1KMT2ATSHR | |
| SCHEMBL6347843 | 0.85 | SLC6A4 (0.43) | ALDH1A1 | |
| SCHEMBL6348954 | 0.84 | SLC6A9 (0.45) | SLC6A9CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6345812 | 0.83 | RORC (0.46) | KMT2AHPGDKDM4E | |
| SCHEMBL6351604 | 0.82 | PSEN1 (0.39) | LMNAHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334087-A1 | CYCLOALKYLFLUOROSULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-08-13 | — | — | EP | claimed |
| WO-2002032858-A1 | CYCLOALKYLFLUOROSULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-04-25 | — | — | WO | claimed |