Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048434 | 0.90 | LMNA (0.31) | LDHALMNA | |
| SCHEMBL12471965 | 0.85 | LMNA (0.32) | LMNA | |
| SCHEMBL28429179 | 0.83 | BLM (0.47) | LMNATBXAS1 | |
| SCHEMBL6888022 | 0.80 | L3MBTL1 (0.47) | LMNAMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL8959221 | 0.79 | TDP1 (0.33) | TBXAS1MEN1KMT2ACA2MAPK1 | |
| SCHEMBL475437 | 0.79 | FOLH1 (0.47) | MEN1GAAKMT2ACA2MAPK1 | |
| SCHEMBL9322083 | 0.79 | — | — | |
| SCHEMBL3919118 | 0.77 | CA1 (0.36) | LMNA | |
| SCHEMBL28300650 | 0.76 | MEN1 (0.33) | MEN1GAAKMT2A | |
| SCHEMBL15384765 | 0.76 | L3MBTL1 (0.40) | LMNAMEN1GAAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913865-B2 | Surface modified encapsulated inorganic resist | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-07-05 | — | — | US | disclosed |
| US-20030099897-A1 | Surface modified encapsulated inorganic resist | MASS INSTITUTE OF TECHNOLOGY (MIT) | 2003-05-29 | — | — | US | disclosed |