Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.58 |
| ▸ | RARG | P13631 | 5/20 | 0.58 |
| ▸ | RARA | P10276 | 5/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | BLVRB | P30043 | 1/20 | 0.58 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922973 | 0.81 | RARB (0.44) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL32685293 | 0.81 | RARB (0.68) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL3935697 | 0.81 | RARB (0.64) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL6937680 | 0.80 | RARB (0.62) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL1615912 | 0.78 | RARB (0.65) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL6447266 | 0.77 | RARB (0.59) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL1614827 | 0.76 | CYP26A1 (0.58) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL8461304 | 0.75 | RARA (0.78) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL1615388 | 0.75 | RARB (0.64) | RARBRARGRARACYP26A1MEN1 | |
| SCHEMBL8461601 | 0.75 | CYP26A1 (0.82) | RARBRARGRARACYP26A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844466-B2 | Alkyl urea retinoid agonists | SYNTEX (U.S.A.) LLC (US) | 2005-01-18 | — | — | US | disclosed |
| EP-1430024-A1 | ALKYL UREA RETINOID AGONISTS I | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-23 | — | — | EP | disclosed |
| US-20030158226-A1 | Alkyl urea retinoid agonists | ROCHE BIOSCIENCE, A DIVISION OF SYNTEX (U.S.A.) LLC | 2003-08-21 | — | — | US | disclosed |
| WO-2003024921-A1 | ALKYL UREA RETINOID AGONISTS I | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158226-A1 | Alkyl urea retinoid agonists | RXRG, RXRA, RXRB | RARB 6/4885RARG 4/4885RARA 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.