Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335390 | 1.00 | CA1 (0.43) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL6344101 | 0.96 | CA1 (0.43) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL6336495 | 0.91 | ALDH1A1 (0.40) | CA1CA2CYP2D6HRH3MEN1 | |
| SCHEMBL6334436 | 0.89 | SIGMAR1 (0.44) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL6334414 | 0.88 | CA7 (0.38) | CA1CA2MEN1KMT2ATSHR | |
| SCHEMBL6337078 | 0.87 | DPP4 (0.37) | CYP2D6HRH3 | |
| SCHEMBL6665870 | 0.87 | ALDH1A1 (0.40) | CA1CA2CYP2D6HRH3KMT2A | |
| SCHEMBL6342896 | 0.87 | HTR6 (0.42) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL6346802 | 0.85 | CA1 (0.40) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL6338274 | 0.85 | SIGMAR1 (0.44) | CA1CA2ACHESIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864266-B2 | 4-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists | SYNTEX (U.S.A.) LLC (US) | 2005-03-08 | — | — | US | claimed |