⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450178 | 1.00 | — | — | |
| SCHEMBL2079893 | 1.00 | DYRK1A (0.41) | — | |
| SCHEMBL20772033 | 0.98 | DYRK1A (0.39) | — | |
| SCHEMBL29259056 | 0.83 | BRD4 (0.31) | — | |
| SCHEMBL6002639 | 0.80 | NUDT1 (0.62) | — | |
| SCHEMBL29241305 | 0.80 | METAP2 (0.32) | — | |
| SCHEMBL30917344 | 0.74 | TDO2 (0.39) | — | |
| SCHEMBL27461853 | 0.72 | EGFR (0.44) | — | |
| SCHEMBL1940496 | 0.71 | KDM4A (0.41) | — | |
| SCHEMBL29624620 | 0.71 | KDM4A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2326 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388599-A1 | TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2025-12-25 | — | — | US | claimed |
| WO-2025111431-A1 | ANTI-CD7 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | LES LABORATOIRES SERVIER (FR) | 2025-05-30 | — | — | WO | claimed |
| WO-2025082069-A1 | COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN | 中国海洋大学 | 2025-04-24 | — | — | WO | claimed |
| EP-4525927-A1 | ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF | Novartis AG (CH) | 2025-03-26 | — | — | EP | claimed |
| CN-119032092-A | Pyrazinone derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-115246822-B | Pyrimidine compound, and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-10-29 | — | — | CN | claimed |
| CN-116239597-B | Pyrimidine pyrrole derivative and medicinal composition and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | claimed |
| US-20240245699-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2024-07-25 | — | — | US | claimed |
| WO-2023225359-A1 | ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2023-11-23 | — | — | WO | claimed |
| CN-114907387-B | Pyrimido pyrrole KRAS inhibitor and preparation method and application thereof | 中山大学 | 2023-11-10 | — | — | CN | claimed |
| CN-1646535-A | Pyrrolopyrimidine derivative | TEIJIN LTD (JP) | 2005-07-27 | — | — | CN | claimed |
| CN-1196704-C | Process for preparing nucleoside metabolism inhibitor and intermediate compound | IND RES LTD (NZ) | 2005-04-13 | — | — | CN | claimed |
| EP-1477490-A1 | PYRROLOPYRIMIDINE DERIVATIVE | TEIJIN LIMITED (JP) | 2004-11-17 | — | — | EP | claimed |
| EP-1477489-A1 | PYRROLOPYRIMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2004-11-17 | — | — | EP | claimed |
| CN-1370171-A | Process for preparing nucleoside metabolism inhibitors | IND RES LTD (NZ) | 2002-09-18 | — | — | CN | claimed |
| EP-0530579-B1 | Condensed pyrimidine derivatives antitumor agents | EISAI CO LTD (JP) | 1998-11-11 | — | — | EP | claimed |
| US-5554615-A | ANTITUMOR | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | claimed |
| EP-0530579-A1 | Condensed pyrimidine derivatives antitumor agents | Eisai Co., Ltd. (JP) | 1993-03-10 | — | — | EP | claimed |
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | claimed |
| EP-0071227-A1 | Anti-leukemic beta-glycosyl C-nucleosides | Sloan-Kettering Institute For Cancer Research (US) | 1983-02-09 | — | — | EP | claimed |