SCHEMBL6345954

SCHEMBL6345954

FC(F)(F)c1nc(-c2cc[c]cc2)no1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 16/20 0.54
HDAC6 Q9UBN7 12/20 0.54
HDAC1 Q13547 4/20 0.50
HDAC8 Q9BY41 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18824381 0.87 HDAC4 (0.66) HDAC4HDAC6HDAC1HDAC8
SCHEMBL29242012 0.84 HDAC6 (0.46) HDAC4HDAC6HDAC1HDAC8
SCHEMBL29277446 0.82 AOC3 (0.44) HDAC4HDAC6
SCHEMBL10552640 0.81 HDAC4 (0.62) HDAC4HDAC6HDAC1HDAC8
SCHEMBL6173198 0.80 HDAC6 (0.46) HDAC4HDAC6HDAC1HDAC8
SCHEMBL27191283 0.80 HDAC6 (0.47) HDAC4HDAC6HDAC1HDAC8
SCHEMBL16217987 0.80 HDAC6 (0.69) HDAC4HDAC6HDAC1HDAC8
SCHEMBL22322456 0.80 HDAC6 (0.63) HDAC4HDAC6HDAC1HDAC8
SCHEMBL29199024 0.79 HDAC6 (0.46) HDAC4HDAC6HDAC1HDAC8
SCHEMBL8123192 0.79 HDAC4 (0.61) HDAC4HDAC6HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112004813-B Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2024-03-29 CN claimed
CN-115697059-A Active compound combinations 拜耳公司 2023-02-03 CN claimed
CN-115697063-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN claimed
CN-112004813-A Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2020-11-27 CN claimed
CN-117813006-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-04-02 CN disclosed
CN-112004813-B Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2024-03-29 CN disclosed
CN-110650956-B Fungicidal oxadiazoles FMC公司 2024-03-08 CN disclosed
CN-117642385-A Pesticidally active cyclic amine compounds 先正达农作物保护股份公司 2024-03-01 CN disclosed
CN-113646304-B Microbiocidal thiazole derivatives 先正达农作物保护股份公司 2024-02-06 CN disclosed
CN-117412961-A Pesticidally active heteroaromatic compounds 先正达农作物保护股份公司 2024-01-16 CN disclosed
CN-117241668-A Microbiocidal quinoline/quinoxaline benzothiazine derivatives 先正达农作物保护股份公司 2023-12-15 CN disclosed
CN-116634874-A Fungicidal oxadiazoles and mixtures thereof FMC公司 2023-08-22 CN disclosed
WO-2021213978-A1 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-10-28 WO disclosed
CN-112154141-A Microbicidal pyridine carboxamide derivatives 先正达参股股份有限公司 2020-12-29 CN disclosed
WO-2020254230-A1 STABILIZED DITHIOCARBAMATE FORMULATIONS BAYER AKTIENGESELLSCHAFT (DE) 2020-12-24 WO disclosed
CN-112004813-A Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2020-11-27 CN disclosed
CN-111094258-A Oxadiazole compound and agricultural and horticultural fungicide 日本曹达株式会社 2020-05-01 CN disclosed
CN-110799035-A Fungicidal compositions 先正达参股股份有限公司 2020-02-14 CN disclosed
US-20050101783-A1 N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide KUREHA CORPORATION (JP) 2005-05-12 US disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050101783-A1 N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide HBZ, ACMSD, HDHD5 HDAC4 1808/4885HDAC6 2773/4885HDAC1 1815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.