Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.64 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.64 |
| ▸ | PLK1 | P53350 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.51 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6350022 | 0.89 | AKR1C2 (0.72) | AKR1C2AKR1C1PLK1MEN1KMT2A | |
| SCHEMBL6353212 | 0.89 | AKR1C2 (0.66) | AKR1C2AKR1C1PLK1MEN1KMT2A | |
| SCHEMBL6346862 | 0.89 | AKR1C2 (0.80) | AKR1C2AKR1C1PLK1MEN1KMT2A | |
| SCHEMBL1307965 | 0.89 | AKR1C2 (0.77) | AKR1C2AKR1C1PLK1MEN1KMT2A | |
| SCHEMBL6352151 | 0.89 | AKR1C2 (0.80) | AKR1C2AKR1C1MEN1KMT2ANPC1 | |
| SCHEMBL6349385 | 0.88 | AKR1C2 (0.71) | AKR1C2AKR1C1PLK1MEN1KMT2A | |
| SCHEMBL6353181 | 0.87 | AKR1C2 (0.77) | AKR1C2AKR1C1PLK1MEN1KMT2A | |
| SCHEMBL6357117 | 0.85 | AKR1C2 (0.61) | AKR1C2AKR1C1PLK1MEN1KMT2A | |
| SCHEMBL6349728 | 0.83 | AKR1C2 (0.62) | AKR1C2AKR1C1PLK1MEN1KMT2A | |
| SCHEMBL6817144 | 0.83 | AKR1C2 (0.63) | AKR1C2AKR1C1PLK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885PLK1 3959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.