Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | SERPINE1 | P05121 | 9/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348324 | 1.00 | CYP1A2 (0.60) | CYP1A2CYP2C19CYP3A4CYP2C9AKR1C4 | |
| SCHEMBL6353139 | 0.88 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP3A4CYP2C9AKR1C4 | |
| SCHEMBL6353138 | 0.88 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP3A4CYP2C9AKR1C4 | |
| SCHEMBL6360629 | 0.87 | CYP1A2 (0.68) | CYP1A2CYP2C19CYP3A4CYP2C9AKR1C4 | |
| SCHEMBL6359750 | 0.80 | SERPINE1 (0.71) | CYP1A2CYP2C19CYP3A4CYP2C9AKR1C4 | |
| SCHEMBL6358679 | 0.79 | AKR1C4 (0.60) | AKR1C4AKR1C3AKR1C2AKR1C1SERPINE1 | |
| SCHEMBL6358675 | 0.79 | AKR1C4 (0.60) | AKR1C4AKR1C3AKR1C2AKR1C1SERPINE1 | |
| SCHEMBL6353083 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP3A4CYP2C9SERPINE1 | |
| SCHEMBL6353081 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP3A4CYP2C9SERPINE1 | |
| SCHEMBL6349319 | 0.76 | SERPINE1 (0.85) | AKR1C4AKR1C3AKR1C2AKR1C1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | CYP1A2 2118/4885CYP2C19 1614/4885CYP3A4 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.