SCHEMBL6348806

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6339189	0.98	ESR1 (0.70)	ESR1ESR2PDCD1CD274APP
	SCHEMBL10145543	0.87	ALDH1A1 (0.61)	ESR1ESR2PDCD1CD274ALDH1A1
	SCHEMBL3893552	0.87	ALDH1A1 (0.61)	ESR1ESR2PDCD1CD274ALDH1A1
	SCHEMBL6338007	0.83	SLC2A1 (0.59)	ESR1ESR2PDCD1CD274APP
	4-Dimethylaminophenol SCHEMBL23467138	0.82	APP (0.61)	ESR1ESR2PDCD1CD274APP
	4-Dimethylaminophenol SCHEMBL224308	0.82	APP (0.73)	APPALDH1A1TSHRALOX15HSD17B10
	4-Dimethylaminophenol SCHEMBL9792507	0.82	APP (0.73)	APPALDH1A1TSHRALOX15HSD17B10
	SCHEMBL26946	0.82	ESR1 (1.00)	ESR1ESR2PDCD1CD274ALDH1A1
	SCHEMBL10593295	0.82	ESR1 (1.00)	ESR1ESR2PDCD1CD274ALDH1A1
	Ammonia Solution, Strong SCHEMBL7989093	0.79	ESR1 (0.94)	ESR1ESR2PDCD1CD274ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.