Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | DDO | Q99489 | 2/20 | 0.47 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31257785 | 0.83 | ALDH1A1 (0.43) | HSD17B1HSD17B2DAODDOCYP1A2 | |
| SCHEMBL27656034 | 0.83 | HSD17B1 (0.53) | HSD17B1HSD17B2DAODDOTRPM4 | |
| SCHEMBL3671771 | 0.80 | CYP1A2 (0.40) | HSD17B1HSD17B2DAODDOCYP1A2 | |
| SCHEMBL5722785 | 0.78 | HPRT1 (0.41) | HSD17B1HSD17B2DAODDOCYP1A2 | |
| SCHEMBL7793914 | 0.78 | GRIN2D (0.61) | HSD17B1HSD17B2TRPM4GRIN2DGRIN2A | |
| SCHEMBL2710690 | 0.77 | HSD17B1 (0.39) | HSD17B1HSD17B2DAODDOTRPM4 | |
| SCHEMBL5179135 | 0.76 | ALDH1A1 (0.45) | HSD17B1HSD17B2CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL21730006 | 0.76 | TRPM4 (0.50) | HSD17B1HSD17B2TRPM4GRIN2DGRIN2A | |
| SCHEMBL4542359 | 0.76 | KDM4E (0.57) | HSD17B1HSD17B2CYP1A2ESR1ESR2 | |
| SCHEMBL30887779 | 0.76 | HSD17B1 (0.53) | HSD17B1HSD17B2NQO2CYP1A2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878659-B2 | Solid catalyst component for olefin polymerization and catalyst | TOHO TITANIUM CO., LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| US-20040072681-A1 | Solid catalyst component for olefin polymerization and catalyst | TOHO TITANIUM CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1260524-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST | Toho Titanium Co., Ltd. (JP) | 2002-11-27 | — | — | EP | disclosed |