Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729402 | 0.85 | ALDH1A1 (0.53) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL7793914 | 0.82 | GRIN2D (0.61) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL7176235 | 0.78 | CYP1A2 (0.46) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL19202198 | 0.76 | TRPM4 (0.46) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL6348334 | 0.76 | DAO (0.52) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL6345832 | 0.76 | CYP1A2 (0.54) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL6346427 | 0.76 | TRPM4 (0.46) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL6349136 | 0.76 | HSD17B1 (0.47) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL10712705 | 0.76 | ALDH1A1 (0.50) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL17049622 | 0.75 | CDK2 (0.55) | TRPM4GRIN2DGRIN2AGRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837038-B1 | DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF | UNIV CALIFORNIA (US) | 2023-02-15 | — | — | EP | disclosed |
| US-20210309802-A1 | DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF | UNITED STATES DEPARTMENT OF ENERGY | 2021-10-07 | — | — | US | disclosed |
| WO-2020037246-A1 | DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309802-A1 | DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF | PARN, PARG, PAM | TRPM4 3995/4885GRIN2D 489/4885GRIN2A 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.