Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 6/20 | 0.60 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.49 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349430 | 0.90 | AKR1C2 (0.75) | PLK1PLK3MAPTAKR1C2AKR1C1 | |
| SCHEMBL6349859 | 0.88 | MAPT (0.76) | PLK1PLK3MAPTAKR1C2AKR1C1 | |
| SCHEMBL6353212 | 0.87 | AKR1C2 (0.66) | PLK1PLK3MAPTAKR1C2AKR1C1 | |
| SCHEMBL4211236 | 0.85 | MAPT (0.59) | PLK1PLK3MAPTAKR1C2AKR1C1 | |
| SCHEMBL6350022 | 0.85 | AKR1C2 (0.72) | PLK1PLK3MAPTAKR1C2AKR1C1 | |
| SCHEMBL6346862 | 0.85 | AKR1C2 (0.80) | PLK1PLK3MAPTAKR1C2AKR1C1 | |
| SCHEMBL6349385 | 0.83 | AKR1C2 (0.71) | PLK1MAPTAKR1C2AKR1C1MEN1 | |
| SCHEMBL4209179 | 0.83 | AKR1C2 (0.56) | PLK1PLK3MAPTAKR1C2AKR1C1 | |
| SCHEMBL6353181 | 0.83 | AKR1C2 (0.77) | PLK1PLK3MAPTAKR1C2AKR1C1 | |
| SCHEMBL4213146 | 0.82 | AKR1C2 (0.61) | PLK1PLK3MAPTAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | PLK1 3959/4885PLK3 2501/4885MAPT 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.