Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443392 | 0.98 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL15443027 | 0.98 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL634058 | 0.98 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL15442983 | 0.98 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL7133197 | 0.96 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL423892 | 0.91 | KMT2A (0.47) | ALDH1A1GAAKMT2ACASP1CYP3A4 | |
| SCHEMBL719931 | 0.91 | — | — | |
| SCHEMBL1218797 | 0.88 | ALDH1A1 (0.39) | ALDH1A1GAAKMT2ACASP1CYP3A4 | |
| SCHEMBL1219520 | 0.84 | KMT2A (0.41) | ALDH1A1GAAKMT2ACASP1CYP3A4 | |
| SCHEMBL11769670 | 0.84 | KMT2A (0.41) | ALDH1A1GAAKMT2ACASP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759483-B | Preparation method of methylamino-substituted alkyl cyclopentanecarboxylate | 浙江瑞博制药有限公司 | 2022-03-11 | — | — | CN | claimed |
| US-11779015-B2 | Pesticide compositions | FUNDACIÓ CENTRE DE REGULACIÓ GENÓMICA (ES) | 2023-10-10 | — | — | US | disclosed |
| CN-110128288-B | Preparation method of amino-substituted cyclopentane alkyl formate derivative | 浙江九洲药业股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-110128288-B | Preparation method of amino-substituted cyclopentane alkyl formate derivative | 浙江九洲药业股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-107759483-B | Preparation method of methylamino-substituted alkyl cyclopentanecarboxylate | 浙江瑞博制药有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-107759483-B | Preparation method of methylamino-substituted alkyl cyclopentanecarboxylate | 浙江瑞博制药有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-107759483-B | Preparation method of methylamino-substituted alkyl cyclopentanecarboxylate | 浙江瑞博制药有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-20200359621-A1 | PESTICIDE COMPOSITIONS | FUNDACIÓ CENTRE DE REGULACIÓ GENÒMICA (ES) | 2020-11-19 | — | — | US | disclosed |
| EP-3713415-A1 | PESTICIDE COMPOSITIONS | Fundació Centre de Regulació Genòmica (ES) | 2020-09-30 | — | — | EP | disclosed |
| WO-2019101890-A1 | PESTICIDE COMPOSITIONS | FUNDACIÓ CENTRE DE REGULACIÓ GENÒMICA (ES) | 2019-05-31 | — | — | WO | disclosed |
| US-20050165201-A1 | Epoxidizing an alpha-halohydrin intermediate from a halide substitution-deesterification of an alpha -hydroxy ester derivative obtained by the coupling reaction of a phenol and a glycidyl ester | BORIACK CLINTON J (US) | 2005-07-28 | — | — | US | disclosed |
| US-20030149219-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | BORIACK CLINTON J (US) | 2003-08-07 | — | — | US | disclosed |
| US-6534621-B2 | Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative | DOW GLOBAL TECHNOLOGIES INC. | 2003-03-18 | — | — | US | disclosed |
| EP-1290058-A2 | PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-03-12 | — | — | EP | disclosed |
| US-20020045707-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2002-04-18 | — | — | US | disclosed |
| WO-2001088013-A2 | PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2001-11-22 | — | — | WO | disclosed |
| EP-0126506-A3 | PREPARATION OF THE ALKYL CYCLOPENTANE-CARBOXYLATES USEFUL AS INTERMEDIATES FOR PREPARING PROSTAGLANDINS | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1985-07-31 | — | — | EP | disclosed |
| EP-0126506-A2 | Preparation of the alkyl cyclopentane-carboxylates useful as intermediates for preparing prostaglandins | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1984-11-28 | — | — | EP | disclosed |
| EP-0126506-A2 | Preparation of the alkyl cyclopentane-carboxylates useful as intermediates for preparing prostaglandins | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1984-11-28 | — | — | EP | disclosed |
| US-4140554-A | Water-rinsable soldering fluid containing a polyamide dispersant | CHEVRON RESEARCH COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200359621-A1 | PESTICIDE COMPOSITIONS | ADH1C, DDT, AKR1C3 | ALDH1A1 35/4885GAA 3742/4885KMT2A 2852/4885 |
| US-11779015-B2 | Pesticide compositions | ADH1C, DDT, AKR1C3 | ALDH1A1 35/4885GAA 3742/4885KMT2A 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.