SCHEMBL635027

SCHEMBL635027

COC(=O)[C@H](C)N(C(=O)c1ccccc1)c1ccc(F)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
PLA2G1B P04054 1/20 0.51
HTT P42858 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ATG4B Q9Y4P1 1/20 0.51
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
MDM4 O15151 2/20 0.44
MDM2 Q00987 2/20 0.44
PTGIR P43119 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
MAPT P10636 1/20 0.39
CASP3 P42574 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
KDM4E B2RXH2 1/20 0.38
TSHR P16473 1/20 0.38
MLYCD O95822 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435442 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL30519772 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL634572 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL55267 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL8827406 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL8541737 0.96 MEN1 (0.48) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL932528 0.94 MEN1 (0.46) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL11284170 0.90 MEN1 (0.46) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL6697896 0.89 HTT (0.43) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL5404448 0.89 NPC1 (0.44) MEN1KMT2APLA2G1BHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090300800-A1 D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation BASF PLANT SCIENCE GMBH (DE) 2009-12-03 US claimed
EP-0407341-B1 Selective herbicidal agent CIBA GEIGY AG (CH) 1995-12-06 EP claimed
US-5217524-A 1,5-diphenyl-1,2,4-triazole-3-carboxylic acid derivatives for the protection of cultivated plants from the phytotoxic action of herbicides CIBA-GEIGY CORPORATION (US) 1993-06-08 US claimed
US-5059239-A Preemergence; postemergence; grains CIBA-GEIGY CORPORATION (US) 1991-10-22 US claimed
EP-0407341-A1 Selective herbicidal agent CIBA-GEIGY AG (CH) 1991-01-09 EP claimed
EP-0310555-A1 Derivatives of 1,5-diphenyl-1,2,4-triazole-3-carboxylic acid for crop protection against the phytotoxic activity of herbicides CIBA-GEIGY AG (CH) 1989-04-05 EP claimed
EP-1727906-B1 IMPROVED CONSTRUCTS FOR MARKER EXCISION BASED ON DUAL-FUNCTION SELECTION MARKER BASF PLANT SCIENCE GMBH (DE) 2012-02-22 EP disclosed
US-20090300800-A1 D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation BASF PLANT SCIENCE GMBH (DE) 2009-12-03 US disclosed
US-20090106856-A1 Selection System for Wheat BASF PLANT SCIENCE GMBH (DE) 2009-04-23 US disclosed
US-20090083883-A1 D-Amino Acid Selection For Soybean BASF PLANT SCIENCE GMBH (DE) 2009-03-26 US disclosed
US-20090038025-A1 Selection system for maize transformation BASF PLANT SCIENCE GMBH (DE) 2009-02-05 US disclosed
CN-101351555-A A new selection system for wheat BASF PLANT SCIENCE GMBH (DE) 2009-01-21 CN disclosed
EP-1996712-A2 D-AMINO ACID SELECTION FOR SOYBEAN BASF Plant Science GmbH (DE) 2008-12-03 EP disclosed
US-5041157-A Protecting soybeans or cereals CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
EP-0407341-A1 Selective herbicidal agent CIBA-GEIGY AG (CH) 1991-01-09 EP disclosed
EP-0378508-A2 Antidotes to modify the resistance of cultivated plants to agrochemical agents CIBA-GEIGY AG (CH) 1990-07-18 EP disclosed
EP-0310555-A1 Derivatives of 1,5-diphenyl-1,2,4-triazole-3-carboxylic acid for crop protection against the phytotoxic activity of herbicides CIBA-GEIGY AG (CH) 1989-04-05 EP disclosed
WO-1987006428-A1 PESTICIDAL CONCENTRATE COMPOSITIONS KEMISK VA^ERK KO^/GE A/S (DK) 1987-11-05 WO disclosed
EP-0243872-A1 Pesticidal concentrate compositions BEROL NOBEL (SUISSE) S.A. (CH) 1987-11-04 EP disclosed
US-4102671-A HERBICIDES SHELL OIL COMPANY (US) 1978-07-25 US disclosed