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SCHEMBL634572

SCHEMBL634572

COC(=O)[C@@H](C)N(C(=O)c1ccccc1)c1ccc(F)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.51
▸ KMT2A Q03164 3/20 0.51
▸ PLA2G1B P04054 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.51
▸ ATG4B Q9Y4P1 1/20 0.51
▸ NPC1 O15118 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ MDM4 O15151 2/20 0.44
▸ MDM2 Q00987 2/20 0.44
▸ PTGIR P43119 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ CASP3 P42574 1/20 0.39
▸ SENP7 Q9BQF6 1/20 0.39
▸ PTGS1 P23219 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ MLYCD O95822 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435442 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL30519772 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL635027 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL55267 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL8827406 1.00 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL8541737 0.96 MEN1 (0.48) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL932528 0.94 MEN1 (0.46) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL11284170 0.90 MEN1 (0.46) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL6697896 0.89 HTT (0.43) MEN1KMT2APLA2G1BHTTNPSR1
SCHEMBL5404448 0.89 NPC1 (0.44) MEN1KMT2APLA2G1BHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337017-A1 HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS Bayer Aktiengesellschaft (DE) 2024-03-20 — — EP claimed
WO-2022152728-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2022-07-21 — — WO claimed
US-20090300800-A1 D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation BASF PLANT SCIENCE GMBH (DE) 2009-12-03 — — US claimed
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides BAYER CROPSCIENCE AG (DE) 2005-04-28 — — US claimed
CN-1589101-A Herbicides containing substituted thien-3-ylsulfonylamino (thio) carbonyltriazolin (thi) one compounds BAYER CROPSCIENCE GMBH (DE) 2005-03-02 — — CN claimed
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-06 — — US claimed
EP-0407341-B1 Selective herbicidal agent CIBA GEIGY AG (CH) 1995-12-06 — — EP claimed
US-5059239-A Preemergence; postemergence; grains CIBA-GEIGY CORPORATION (US) 1991-10-22 — — US claimed
EP-0407341-A1 Selective herbicidal agent CIBA-GEIGY AG (CH) 1991-01-09 — — EP claimed
EP-4378314-A2 HERBICIDAL COMPOSITIONS Bayer AG (DE) 2024-06-05 — — EP disclosed
CN-114340393-B Herbicidal composition 拜耳公司 2024-05-24 — — CN disclosed
EP-4337017-A1 HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS Bayer Aktiengesellschaft (DE) 2024-03-20 — — EP disclosed
US-20230032505-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2023-02-02 — — US disclosed
EP-3890488-B1 HERBICIDAL COMBINATIONS BAYER AG (DE) 2023-01-04 — — EP disclosed
EP-1429612-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE Bayer CropScience AG (DE) 2004-06-23 — — EP disclosed
WO-2003026426-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE BAYER CROPSCIENCE AG (DE) 2003-04-03 — — WO disclosed
WO-1998051153-A1 HERBICIDAL METHODS AND DERIVATIVES RHONE-POULENC AGRICULTURE LTD. (GB) 1998-11-19 — — WO disclosed
EP-0663795-B1 SOLID CROP PROTECTION FORMULATION SHELL INT RESEARCH (NL) 1998-08-12 — — EP disclosed
EP-0407341-B1 Selective herbicidal agent CIBA GEIGY AG (CH) 1995-12-06 — — EP disclosed
EP-0407341-A1 Selective herbicidal agent CIBA-GEIGY AG (CH) 1991-01-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230032505-A1 HERBICIDAL COMPOSITIONS DDT, GUSB, HDHD5 MEN1 4490/4885KMT2A 990/4885PLA2G1B 793/4885
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides AADAC, NOTUM, NAAA MEN1 4403/4885KMT2A 385/4885PLA2G1B 2733/4885
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one DDT, TARS2, CBR3 MEN1 4114/4885KMT2A 1446/4885PLA2G1B 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.