SCHEMBL6697896

SCHEMBL6697896

COC(=O)C(C)N(C(=O)c1ccccc1)c1ccc(F)c(Cl)c1.COC(=O)[C@H](C)N(Oc1ccc(F)c(Cl)c1)C(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.43
MEN1 O00255 1/20 0.43
PLA2G1B P04054 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
MDM2 Q00987 3/20 0.38
MDM4 O15151 2/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
C5AR1 P21730 2/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
TAS1R2 Q8TE23 1/20 0.34
PTGIR P43119 1/20 0.34
NR1H4 Q96RI1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5399890 0.94 HTT (0.42) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL5399887 0.94 HTT (0.42) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL8827406 0.89 MEN1 (0.51) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL29435442 0.89 MEN1 (0.51) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL635027 0.89 MEN1 (0.51) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL55267 0.89 MEN1 (0.51) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL634572 0.89 MEN1 (0.51) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL30519772 0.89 MEN1 (0.51) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL8541737 0.86 MEN1 (0.48) HTTMEN1PLA2G1BKMT2ANPSR1
SCHEMBL932528 0.84 MEN1 (0.46) HTTMEN1PLA2G1BKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC HTT 646/4885MEN1 4777/4885PLA2G1B 3021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.