SCHEMBL6347648

SCHEMBL6347648

CC(=O)c1ccc(Sc2ccc(OCc3ccccc3)cc2)nc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.64
ALDH1A1 P00352 1/20 0.55
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
NR4A1 P22736 1/20 0.52
NR4A2 P43354 1/20 0.52
NR4A3 Q92570 1/20 0.52
MAOA P21397 2/20 0.51
PARP10 Q53GL7 1/20 0.50
SRD5A2 P31213 1/20 0.49
PLA2G4B P0C869 1/20 0.47
EGFR P00533 1/20 0.46
LTB4R Q15722 1/20 0.46
LTB4R2 Q9NPC1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6341711 0.90 NR4A2 (0.62) MAOBALDH1A1SMN1; SMN2NR4A1NR4A2
SCHEMBL6339246 0.88 MAOB (0.51) MAOBSMN1; SMN2NR4A1NR4A2NR4A3
SCHEMBL6350325 0.84 MAOB (0.47) MAOBL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL6347392 0.81 FFAR1 (0.50) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL42302 0.80 MAOB (1.00) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL14571017 0.79 ALDH1A1 (0.80) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL6346472 0.79 MAOB (0.69) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL29953258 0.76 HPGD (0.59) ALDH1A1L3MBTL1
SCHEMBL6337667 0.76 MAOB (0.90) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL9126144 0.76 MAOB (0.90) MAOBALDH1A1HTTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1907960-A Anthranilic acid derivatives TEIJIN LTD (JP) 2007-02-07 CN disclosed
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 MAOB 2681/4885ALDH1A1 250/4885HTT 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.