Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PCNA | P12004 | 2/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498158 | 0.84 | — | — | |
| SCHEMBL6350388 | 0.84 | KMT2A (0.51) | NR1I2PPARGAGTR2MEN1BLM | |
| SCHEMBL5574192 | 0.82 | KMT2A (0.52) | NR1I2PPARGAGTR2MEN1BLM | |
| SCHEMBL230513 | 0.82 | KMT2A (0.52) | NR1I2PPARGAGTR2MEN1BLM | |
| SCHEMBL282065 | 0.82 | KMT2A (0.52) | NR1I2PPARGAGTR2MEN1BLM | |
| SCHEMBL10537170 | 0.80 | BLM (0.41) | NR1I2PPARGAGTR2MEN1BLM | |
| SCHEMBL10495232 | 0.80 | BLM (0.41) | NR1I2PPARGAGTR2MEN1BLM | |
| Hydrochloric Acid SCHEMBL10529768 | 0.79 | BLM (0.41) | NR1I2PPARGAGTR2MEN1BLM | |
| SCHEMBL16390915 | 0.72 | KMT2A (0.47) | NR1I2PPARGAGTR2MEN1BLM | |
| SCHEMBL10690644 | 0.69 | SCN9A (0.44) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070042962-A1 | Peptide dependent upregulation of telomerase expression | ISCHEMIX, INC. | 2007-02-22 | — | — | US | disclosed |
| WO-2003066814-A2 | PEPTIDE-DEPENDENT UPREGULATION OF TELOMERASE EXPRESSION | CEREMEDIX, INC. (US) | 2003-08-14 | — | — | WO | disclosed |
| US-5196349-A | Labeled antibody, thyroxine, triiodothyronine, immobilized, modified by succinylation | CIBA CORNIGN DIAGNOSTICS CORP. (US) | 1993-03-23 | — | — | US | disclosed |