SCHEMBL635057

SCHEMBL635057

C=CCC(=C)c1ccc2cc3ccccc3cc2c1P(=O)(O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 1/20 0.35
PTK2B Q14289 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
PKM P14618 2/20 0.32
MAPK1 P28482 2/20 0.32
KMT2A Q03164 2/20 0.32
EGFR P00533 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
JAK1 P23458 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL635275 0.87 PTK2B (0.43) KDM4EALDH1A1GAAPTK2BL3MBTL1
SCHEMBL635990 0.76 L3MBTL1 (0.38) KDM4EALDH1A1PTK2BL3MBTL1MEN1
SCHEMBL6402797 0.76 ALDH1A1 (0.50) KDM4EALDH1A1GAAPTK2BL3MBTL1
SCHEMBL635628 0.76 CYP2D6 (0.42) KDM4EALDH1A1GAAMEN1MAPT
SCHEMBL634170 0.76 ALDH1A1 (0.38) KDM4EALDH1A1GAAPTK2BL3MBTL1
SCHEMBL3282140 0.71 PTPN1 (0.41) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL21164727 0.71 ALDH1A1 (0.42) KDM4EALDH1A1GAAPTK2BL3MBTL1
SCHEMBL634284 0.70 CYP3A4 (0.40) ALDH1A1PTK2BL3MBTL1MAPTKMT2A
SCHEMBL3281191 0.70 ALDH1A1 (0.40) KDM4EALDH1A1GAAL3MBTL1MEN1
SCHEMBL4793505 0.67 MEN1 (0.31) KDM4EALDH1A1MEN1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8137860-B2 Polymer electrolyte membrane for solid polymer fuel cell, membrane-electrode assembly and fuel cell KURARAY CO., LTD. (JP) 2012-03-20 US disclosed
EP-1840993-B1 POLYMER ELECTROLYTE MEMBRANE FOR SOLID POLYMER FUEL CELL, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL KURARAY CO (JP) 2012-02-22 EP disclosed
EP-1852928-B1 ION-CONDUCTIVE BINDER, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL KURARAY CO LTD KURASHIKI PLANT (JP) 2011-11-16 EP disclosed
US-20110265032-A1 DISPLAY OF FILTERED DATA VIA ORDERED VALUES MICROSOFT CORPORATION (US) 2011-10-27 US disclosed
US-20100233569-A1 ELECTROLYTE MULTILAYER MEMBRANE FOR SOLID POLYMER FUEL CELL, MEMBRANE-ELECTRODE ASSEMBLY, AND FUEL CELL KURARAY CO., LTD (JP) 2010-09-16 US disclosed
US-7740968-B2 Ion-conductive binder membrane-electrode assembly and fuel cell KURARAY CO., LTD. (JP) 2010-06-22 US disclosed
US-20090123804-A1 Polymer Electrolyte Membrane For Solid Polymer Fuel Cell, Membrane-Electrode Assembly And Fuel Cell KURARAY CO., LTD (JP) 2009-05-14 US disclosed
EP-1978584-A1 ELECTROLYTE MULTILAYER MEMBRANE FOR SOLID POLYMER FUEL CELL, MEMBRANE-ELECTRODE ASSEMBLY, AND FUEL CELL Kuraray Co., Ltd. (JP) 2008-10-08 EP disclosed
US-20080113244-A1 Ion-Conductive Binder Membrane-Electrode Assembly and Fuel Cell KURARAY CO., LTD (JP) 2008-05-15 US disclosed
EP-1852928-A1 ION-CONDUCTIVE BINDER, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Kuraray Co., Ltd., Kurashiki Plant (JP) 2007-11-07 EP disclosed
EP-1840993-A1 POLYMER ELECTROLYTE MEMBRANE FOR SOLID POLYMER FUEL CELL, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL KURARAY CO., LTD. (JP) 2007-10-03 EP disclosed