SCHEMBL635088

SCHEMBL635088

CNC(=O)c1cccc(C)c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.50
GAA P10253 1/20 0.48
HPGD P15428 5/20 0.45
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CD44 P16070 1/20 0.43
POLB P06746 1/20 0.42
MYC P01106 1/20 0.42
HSD17B10 Q99714 3/20 0.41
AR P10275 1/20 0.41
MTNR1A P48039 1/20 0.41
HTT P42858 3/20 0.39
MAPT P10636 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
RAB9A P51151 1/20 0.39
HDAC8 Q9BY41 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31038153 1.00 PLK1 (0.50) PLK1GAAHPGDKDM4EALDH1A1
Hydrochloric Acid SCHEMBL31400038 0.98 PLK1 (0.49) PLK1GAAHPGDKDM4EALDH1A1
SCHEMBL7322497 0.85 HDAC8 (0.47) GAAHPGDKDM4EALDH1A1SMN1; SMN2
SCHEMBL5252014 0.82 PLK1 (0.52) PLK1GAAHPGDKDM4EALDH1A1
SCHEMBL31301322 0.81 MEN1 (0.51) HPGDKDM4EALDH1A1SMN1; SMN2POLB
SCHEMBL28023692 0.81 PTGS2 (0.46) HPGDKDM4EALDH1A1SMN1; SMN2CD44
SCHEMBL11745378 0.81 POLB (0.65) HPGDKDM4EALDH1A1SMN1; SMN2POLB
SCHEMBL28089985 0.81 PLK1 (0.50) PLK1GAAHPGDKDM4EALDH1A1
SCHEMBL465699 0.81 G6PD (0.55) PLK1GAAHPGDKDM4EALDH1A1
SCHEMBL12818997 0.80 MAPT (0.49) HPGDKDM4EALDH1A1SMN1; SMN2CD44

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676908-A1 PHOTOCHEMICAL SYSTEMS AND METHODS FOR PREPARING CYANOBENZAMIDES FMC Corporation (US) 2026-01-14 EP claimed
CN-120058546-A 2-Amino-5-chloro-N, 3-dimethylbenzamide production process 九江善水科技股份有限公司 2025-05-30 CN claimed
CN-120037937-A Catalyst for preparing 2-amino-N, 3-dimethylbenzamide by continuous hydrogenation and preparation method and application thereof 湖南长炼新材料科技股份公司 2025-05-27 CN claimed
CN-119874556-A Synthesis method of 2-amino-N, 3-dimethylbenzamide 北京弗莱明科技有限公司 2025-04-25 CN claimed
WO-2024186513-A1 PHOTOCHEMICAL SYSTEMS AND METHODS FOR PREPARING CYANOBENZAMIDES FMC CORPORATION (US) 2024-09-12 WO claimed
CN-118439967-A Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 宁夏贝利特生物科技有限公司 2024-08-06 CN claimed
CN-115197085-B Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 九江善水科技股份有限公司 2024-02-13 CN claimed
CN-116983927-B System and method for continuously producing chlorantraniliprole 天津凯莱英医药科技发展有限公司 2024-01-19 CN claimed
CN-116983927-A System and method for continuously producing chlorantraniliprole 天津凯莱英医药科技发展有限公司 2023-11-03 CN claimed
CN-115197085-A Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 九江善水科技股份有限公司 2022-10-18 CN claimed
CN-113480518-A Method for synthesizing chlorantraniliprole 江西汇和化工有限公司 2021-10-08 CN claimed
WO-2021033172-A1 PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE EUROFINS ADVINUS LIMITED (IN) 2021-02-25 WO claimed
CN-101492387-B Preparation for 2-amino-5-chlorine-N,3-dimethyl benzamide UNIV ZHEJIANG 2012-07-25 CN claimed
CN-122102936-A Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 2026-05-29 CN disclosed
CN-224236783-U Hydrogenation reaction device for 2-nitro-N, 3-dimethylbenzamide 内蒙古鲲鹏新材料有限公司 2026-05-15 CN disclosed
US-12590070-B2 Adamantane derivatives as inhibitors of focal adhesion kinase SAMJIN PHARMACEUTICAL CO., LTD. (KR) 2026-03-31 US disclosed
EP-1828164-A1 METHOD FOR PREPARING N-PHENYLPYRAZOLE-1-CARBOXAMIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-09-05 EP disclosed
EP-1757594-A1 QUINAZOLINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-02-28 EP disclosed
WO-2006062978-A1 METHOD FOR PREPARING N-PHENYLPYRAZOLE-1-CARBOXAMIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-15 WO disclosed
US-5726319-A Biphenyl substituted dipeptide analogs promote release of growth hormone MERCK & CO., INC. (US) 1998-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590070-B2 Adamantane derivatives as inhibitors of focal adhesion kinase PTK2, CTTN, ADGRF1 PLK1 700/4885GAA 4319/4885HPGD 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.