Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 9/20 | 0.58 |
| ▸ | PPARD | Q03181 | 9/20 | 0.58 |
| ▸ | PPARA | Q07869 | 8/20 | 0.58 |
| ▸ | CPT2 | P23786 | 2/20 | 0.54 |
| ▸ | CPT1A | P50416 | 2/20 | 0.54 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352776 | 0.95 | PPARG (0.58) | MAPTPPARGPPARDPPARACPT2 | |
| SCHEMBL6351073 | 0.95 | MAPT (0.60) | MAPTPPARGPPARDPPARACPT2 | |
| SCHEMBL6356719 | 0.91 | PPARG (0.64) | MAPTPPARGPPARDPPARAALB | |
| SCHEMBL6351428 | 0.91 | PPARG (0.65) | MAPTPPARGPPARDPPARAALB | |
| SCHEMBL6349561 | 0.89 | PPARG (0.64) | MAPTPPARGPPARDPPARAALB | |
| SCHEMBL6351559 | 0.89 | PPARG (0.59) | MAPTPPARGPPARDPPARAALB | |
| SCHEMBL6351952 | 0.88 | PPARG (0.58) | MAPTPPARGPPARDPPARAALB | |
| SCHEMBL6350657 | 0.86 | PPARG (0.59) | MAPTPPARGPPARDPPARAALB | |
| SCHEMBL6351880 | 0.86 | PPARG (0.57) | MAPTPPARGPPARDPPARAALB | |
| SCHEMBL6349496 | 0.85 | PPARG (0.59) | MAPTPPARGPPARDPPARAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MAPT 4753/4885PPARG 3572/4885PPARD 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.