SCHEMBL6351571

SCHEMBL6351571

CCC1CCCCN1S(=O)(=O)c1ccc(C(=O)Nc2ccc(C#N)cc2C(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.61
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
TP53 P04637 4/20 0.53
LMNA P02545 3/20 0.53
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALOX15 P16050 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
USP2 O75604 1/20 0.53
MAPT P10636 5/20 0.50
PSEN1 P49768 1/20 0.48
PSEN2 P49810 1/20 0.48
APH1B Q8WW43 1/20 0.48
NCSTN Q92542 1/20 0.48
APH1A Q96BI3 1/20 0.48
PSENEN Q9NZ42 1/20 0.48
HPGD P15428 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6352917 0.91 TP53 (0.51) ALBMEN1KMT2ATP53LMNA
SCHEMBL6360195 0.90 ALB (0.63) ALBMEN1KMT2ATP53LMNA
SCHEMBL6351250 0.89 ALB (0.60) ALBALDH1A1
SCHEMBL6352004 0.86 ALB (0.65) ALBMEN1KMT2ATP53LMNA
SCHEMBL6359070 0.85 ALB (0.67) ALBMEN1KMT2ATP53LMNA
SCHEMBL6821795 0.83 KMT2A (0.43) ALBMEN1KMT2ATP53LMNA
SCHEMBL6349310 0.82 ALB (0.83) ALBMEN1KMT2ATP53LMNA
SCHEMBL6352010 0.81 ALB (0.81) ALBMEN1KMT2ATP53LMNA
SCHEMBL6357952 0.80 ALB (0.83) ALBMEN1KMT2ATP53LMNA
SCHEMBL6355503 0.80 ALB (0.51) ALBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050113450-A1 Antibacterial agents PHARMACIA & UPJOHN COMPANY 2005-05-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113450-A1 Antibacterial agents CLPP, SPOUT1, SAMHD1 ALB 1682/4885MEN1 3274/4885KMT2A 3645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.