Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6339813 | 0.86 | F10 (0.38) | ROCK2 | |
| Hydrochloric Acid SCHEMBL6342430 | 0.85 | F10 (0.38) | ROCK2 | |
| SCHEMBL6342009 | 0.83 | NAMPT (0.43) | NAMPTKCNK3CNR1CNR2DCAF1 | |
| SCHEMBL6339644 | 0.81 | NAMPT (0.36) | NAMPTKCNK3CNR1CNR2ROCK2 | |
| SCHEMBL6350201 | 0.80 | ROCK2 (0.42) | NAMPTKCNK3ROCK2GPR139ROCK1 | |
| SCHEMBL6343785 | 0.78 | F10 (0.42) | ROCK2 | |
| SCHEMBL6341179 | 0.78 | NAMPT (0.41) | NAMPTKCNK3CNR1CNR2DCAF1 | |
| SCHEMBL6341178 | 0.78 | NAMPT (0.40) | NAMPTKCNK3CNR1CNR2DCAF1 | |
| Hydrochloric Acid SCHEMBL6349095 | 0.78 | F10 (0.41) | ROCK2 | |
| SCHEMBL6554526 | 0.74 | NAMPT (0.43) | NAMPTKCNK3ROCK2GPR139ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838565-B2 | Substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM (DE) | 2004-07-15 | — | — | US | disclosed |
| WO-2004013128-A1 | NOVEL SUBSTITUTED BENZAMIDES PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM (DE) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | F11, F12, SERPINC1 | NAMPT 1501/4885KCNK3 2469/4885CNR1 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.