Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 10/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351926 | 1.00 | OXTR (0.39) | OXTRCMA1CTRCGPR34ALDH1A1 | |
| SCHEMBL6347131 | 0.95 | POLB (0.39) | ALDH1A1CAPN1POLB | |
| SCHEMBL6347128 | 0.95 | POLB (0.39) | ALDH1A1CAPN1POLB | |
| SCHEMBL6348272 | 0.90 | CAPN1 (0.40) | ALDH1A1CAPN1POLB | |
| SCHEMBL6348278 | 0.90 | CAPN1 (0.40) | ALDH1A1CAPN1POLB | |
| SCHEMBL6358276 | 0.85 | POLB (0.35) | OXTRCMA1CTRCGPR34ALDH1A1 | |
| SCHEMBL6356914 | 0.83 | POLB (0.38) | ALDH1A1CAPN1POLB | |
| SCHEMBL6356918 | 0.83 | POLB (0.38) | ALDH1A1CAPN1POLB | |
| SCHEMBL6348393 | 0.80 | POLB (0.38) | ALDH1A1POLB | |
| SCHEMBL6350484 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960575-B2 | For use as inhibitors of chymase | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040097496-A1 | Novel thiazine derivatives | SANTEN PHARMACEUTICAL CO.,LTD. (JP) | 2004-05-20 | — | — | US | disclosed |
| US-6713472-B1 | 2-OXO-1,2,3,4-TETRAHYDROPYRAZINE DERIVATIVES; CHYMASE INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097496-A1 | Novel thiazine derivatives | CMA1, TPSD1, HRH4 | OXTR 964/4885CMA1 1/4885CTRC 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.