Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 10/20 | 0.61 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.50 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352046 | 1.00 | SERPINE1 (0.61) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6358675 | 0.93 | AKR1C4 (0.60) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6358679 | 0.93 | AKR1C4 (0.60) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6352208 | 0.79 | SERPINE1 (0.58) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6352203 | 0.79 | SERPINE1 (0.58) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6351321 | 0.79 | SERPINE1 (0.89) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6359728 | 0.78 | SERPINE1 (0.57) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6359726 | 0.78 | SERPINE1 (0.57) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL420616 | 0.76 | SERPINE1 (1.00) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL421010 | 0.74 | SERPINE1 (1.00) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SERPINE1 1929/4885AKR1C4 3065/4885AKR1C3 3288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.