Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GSDMD | P57764 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.36 |
| ▸ | PHGDH | O43175 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL8672659 | 0.93 | TP53 (0.42) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL48383 | 0.88 | CA12 (0.46) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL213880 | 0.85 | CA12 (0.43) | EHMT2EHMT1ABCB11HTTGSDMD | |
| Hydrochloric Acid SCHEMBL21359740 | 0.85 | CA12 (0.43) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL1882185 | 0.85 | CA12 (0.43) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL25284943 | 0.85 | CA12 (0.43) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL1887058 | 0.85 | CA12 (0.43) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL11148937 | 0.85 | CA12 (0.43) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL43744 | 0.85 | CA12 (0.43) | EHMT2EHMT1ABCB11HTTGSDMD | |
| SCHEMBL8968072 | 0.85 | CA12 (0.43) | EHMT2EHMT1ABCB11HTTGSDMD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659056-A | Holmium complex luminescent material and preparation method and application thereof | 北京石油化工学院 | 2024-03-08 | — | — | CN | claimed |
| CN-115429780-A | Use of disulfiram for protecting gastrointestinal tissue against damage caused by ionizing radiation | 中国人民解放军军事科学院军事医学研究院 | 2022-12-06 | — | — | CN | claimed |
| CN-102179066-B | Method for extracting and separating ions in two valence states of the same element in three phases | INST PROCESS ENG CAS | 2013-10-16 | — | — | CN | claimed |
| CN-102179066-A | Method for extracting and separating ions in two valence states of the same element in three phases | INST PROCESS ENG CAS | 2011-09-14 | — | — | CN | claimed |
| CN-101445699-B | High temperature resistant powder coating | DUBANG HUAJIA CHEMICAL CO LTD | 2011-05-25 | — | — | CN | claimed |
| CN-101445699-A | High temperature resistant powder coating | DUBANG HUAJIA CHEMICAL CO LTD (CN) | 2009-06-03 | — | — | CN | claimed |
| US-4803051-A | METAL ANALYSIS USING ADSORBED VOLATILE METAL COMPLEXES FORMED FROM REAGENT AND SAMPLE | BODENSEEWERK PERKIN-ELMER & CO., GMBH (DE) | 1989-02-07 | — | — | US | claimed |
| JP-3141118-A | — | — | None | — | — | JP | disclosed |
| US-12567515-B2 | Conductive film, touch panel, photosensitive resin composition, and method of manufacturing conductive film | FUJIFILM CORPORATION (JP) | 2026-03-03 | — | — | US | disclosed |
| US-12515253-B2 | Compositions, comprising silver nanoplatelets | BASF SE (DE) | 2026-01-06 | — | — | US | disclosed |
| US-12410144-B2 | Triazinane derivatives and methods of making them | FLEXSYS AMERICA L.P. (US) | 2025-09-09 | — | — | US | disclosed |
| US-20250160193-A1 | CONJUGATED POLYMERS AS HOLE TRANSPORT MATERIALS FOR ENHANCED THERMAL STABILITY IN OPTOELECTRONIC DEVICES | U. S. DEPARTMENT OF ENERGY | 2025-05-15 | — | — | US | disclosed |
| US-12208447-B2 | Compositions, comprising silver nanoplatelets | BASF SE (DE) | 2025-01-28 | — | — | US | disclosed |
| US-4636245-A | Herbicidal tetrahydrothiopyran-2,4-dione derivatives, compositions, and method of use therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-13 | — | — | US | disclosed |
| US-4585628-A | OXIDATION, COM-LEXING, SOLVENT EXTRACTION | AMERICAN CYANAMID COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| US-4547554-A | After-chlorinated ethylene/butene-1 copolymer and process for its production | OSAKA SODA CO., LTD. (JP) | 1985-10-15 | — | — | US | disclosed |
| US-4148795-A | Dithiocarbamate ester bactericides and fungicides | AMERICAN CYANAMID COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4038288-A | DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-4036650-A | SILVER SALT, SILVER HALIDE, REDUCING AGENT | CANON KABUSHIKI KAISHA (JA) | 1977-07-19 | — | — | US | disclosed |
| US-4011230-A | DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410144-B2 | Triazinane derivatives and methods of making them | CBR3, CBR1, HDAC3 | EHMT2 1033/4885EHMT1 1340/4885ABCB11 2331/4885 |
| US-12567515-B2 | Conductive film, touch panel, photosensitive resin composition, and method of manufacturing conductive film | TAS1R2, TAS1R3, TAS1R1 | EHMT2 1165/4885EHMT1 1235/4885ABCB11 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.