Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608616 | 0.87 | MAPT (0.38) | ALDH1A1MAPTL3MBTL1APPIDH1 | |
| SCHEMBL29189704 | 0.80 | CYP1A2 (0.45) | ALDH1A1MAPTUSP2HPGDAPP | |
| SCHEMBL443835 | 0.73 | MAPT (0.40) | ALDH1A1MAPTAPPTSHRMMP1 | |
| SCHEMBL95799 | 0.71 | LTA4H (0.42) | ALDH1A1APPLMNACYP3A4 | |
| SCHEMBL95929 | 0.70 | LTA4H (0.42) | ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL4732470 | 0.68 | DNM1 (0.44) | ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL7980722 | 0.68 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1 | |
| SCHEMBL7194368 | 0.68 | DNM1 (0.44) | ALDH1A1LMNATSHRCYP3A4 | |
| Benzene SCHEMBL28134111 | 0.68 | TSHR (0.53) | ALDH1A1MAPTL3MBTL1TDP1USP2 | |
| SCHEMBL27434469 | 0.67 | FFAR1 (0.53) | ALDH1A1MAPTTDP1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288461-A1 | Polymerization catalysts for producing polymers with low levels of long chain branching | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. | 2005-12-29 | — | — | US | disclosed |