Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 4/20 | 0.65 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.65 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357874 | 0.94 | AKR1C2 (0.63) | AKR1C2AKR1C1AKR1C4AKR1C3NPC1 | |
| SCHEMBL6352294 | 0.91 | AKR1C2 (0.70) | AKR1C2AKR1C1AKR1C4AKR1C3NPC1 | |
| SCHEMBL5950059 | 0.91 | MEN1 (0.73) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL1307097 | 0.89 | AKR1C2 (0.76) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6350354 | 0.88 | AKR1C2 (0.67) | AKR1C2AKR1C1AKR1C4AKR1C3NPC1 | |
| SCHEMBL6351451 | 0.86 | MAPT (0.57) | AKR1C2AKR1C1AKR1C4AKR1C3NPC1 | |
| SCHEMBL6352936 | 0.86 | AKR1C2 (0.74) | AKR1C2AKR1C1AKR1C4AKR1C3NPC1 | |
| SCHEMBL6349179 | 0.84 | AKR1C2 (0.62) | AKR1C2AKR1C1AKR1C4AKR1C3NPC1 | |
| SCHEMBL6347574 | 0.84 | AKR1C2 (0.61) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6350738 | 0.84 | AKR1C2 (0.61) | AKR1C2AKR1C1AKR1C4AKR1C3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885AKR1C4 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.