Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344113 | 0.86 | MEN1 (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL13053725 | 0.83 | ALDH1A1 (0.47) | MEN1ALDH1A1KMT2AHRH3 | |
| SCHEMBL6354590 | 0.76 | ALDH1A1 (0.47) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3283589 | 0.72 | ALDH1A1 (0.46) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19755650 | 0.66 | ALDH1A1 (0.62) | MEN1ALDH1A1KMT2AHRH3 | |
| SCHEMBL21111119 | 0.66 | ALDH1A1 (1.00) | MEN1ALDH1A1KMT2AHRH3 | |
| SCHEMBL3643462 | 0.65 | — | — | |
| SCHEMBL27085534 | 0.63 | — | — | |
| SCHEMBL26823710 | 0.63 | — | — | |
| SCHEMBL21111146 | 0.62 | ALDH1A1 (0.79) | MEN1ALDH1A1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020077316-A1 | Sulfide and disulfide compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS, INC. | 2002-06-20 | — | — | US | claimed |
| US-20050020694-A1 | Sulfide and disulfide compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS, INC. | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077316-A1 | Sulfide and disulfide compounds and compositions for cholesterol management and related uses | GSS, IAPP, STS | MEN1 3008/4885ALDH1A1 2827/4885KMT2A 3706/4885 |
| US-20050020694-A1 | Sulfide and disulfide compounds and compositions for cholesterol management and related uses | GSS, STS, CBS | MEN1 2869/4885ALDH1A1 2643/4885KMT2A 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.