Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA4 | P22748 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748046 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDALDH1A1KMT2APPARG | |
| SCHEMBL5746828 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDALDH1A1KMT2APPARG | |
| SCHEMBL27754688 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDALDH1A1KMT2APPARG | |
| SCHEMBL27734620 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDALDH1A1KMT2APPARG | |
| SCHEMBL5747494 | 0.89 | CXCR3 (0.47) | SMN1; SMN2HPGDKMT2APPARGPPARD | |
| SCHEMBL5749321 | 0.87 | HSD11B1 (0.46) | SMN1; SMN2HPGDALDH1A1KMT2APPARG | |
| SCHEMBL5746954 | 0.86 | NR1H2 (0.47) | SMN1; SMN2HPGDPPARGPPARDPPARA | |
| SCHEMBL6349119 | 0.85 | GCKR (0.43) | ALDH1A1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL5797656 | 0.85 | GCKR (0.43) | ALDH1A1KMT2AF13A1TGM2TGM1 | |
| SCHEMBL5748378 | 0.85 | GCKR (0.43) | ALDH1A1KMT2AF13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234046-A1 | Aryl sulfonamide and sulfonyl compounds as modulators of PPAR and methods of treating metabolic disorders | KALYPSYS, INC. (US) | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234046-A1 | Aryl sulfonamide and sulfonyl compounds as modulators of PPAR and methods of treating metabolic disorders | PPARA, PPARG, PPARD | SMN1; SMN2 2173/4885HPGD 1108/4885ALDH1A1 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.