Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 13/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6362639 | 0.93 | P2RX7 (0.53) | P2RX7PTGER1 | |
| SCHEMBL6357184 | 0.92 | P2RX7 (0.66) | P2RX7TRPA1SIGMAR1PTGER1 | |
| SCHEMBL6359009 | 0.92 | P2RX7 (0.65) | P2RX7TRPA1SIGMAR1PTGER1 | |
| SCHEMBL6357369 | 0.91 | P2RX7 (0.64) | P2RX7TRPA1SIGMAR1PTGER1 | |
| SCHEMBL6359682 | 0.91 | P2RX7 (0.52) | P2RX7PTGER1 | |
| SCHEMBL6357702 | 0.91 | PTGER1 (0.54) | P2RX7PTGER1 | |
| SCHEMBL6357286 | 0.90 | P2RX7 (0.62) | P2RX7TRPA1SIGMAR1PTGER1 | |
| SCHEMBL6362756 | 0.90 | P2RX7 (0.62) | P2RX7TRPA1SIGMAR1PTGER1 | |
| SCHEMBL6357280 | 0.90 | PTGER1 (0.53) | P2RX7PTGER1 | |
| SCHEMBL6354516 | 0.90 | P2RX7 (0.62) | P2RX7TRPA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | claimed |
| EP-1438973-A1 | REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-21 | — | — | EP | claimed |
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1438973-A1 | REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | TFAM, CYP11B2, CYP11B1 | P2RX7 448/4885TRPA1 708/4885SIGMAR1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.