Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | PPIA | P62937 | 2/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | STK10 | O94804 | 1/20 | 0.51 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.51 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359813 | 0.90 | CTSV (0.56) | CTSVCTSLSIRT2MAOBBCHE | |
| SCHEMBL6098127 | 0.89 | CTSV (0.65) | CTSVCTSLSIRT2MAOBBCHE | |
| SCHEMBL3823697 | 0.85 | RXRA (0.69) | MAOBRXRARXRBRXRGBCHE | |
| SCHEMBL21810515 | 0.85 | PPIA (0.76) | CTSVCTSLMAOBPPIARXRA | |
| SCHEMBL7713159 | 0.84 | MAOB (0.64) | MAOBRXRARXRBRXRGBCHE | |
| SCHEMBL6360679 | 0.82 | CTSV (0.66) | CTSVCTSLSIRT2MAOBBCHE | |
| SCHEMBL11920270 | 0.81 | BCHE (0.58) | CTSVCTSLSIRT2MAOBBCHE | |
| Methyl Alcohol SCHEMBL27542849 | 0.81 | RXRA (0.68) | MAOBRXRARXRBRXRGBCHE | |
| SCHEMBL3594258 | 0.81 | CTSV (0.56) | CTSVCTSLSIRT2MAOBBCHE | |
| SCHEMBL27438029 | 0.81 | CTSV (0.56) | CTSVCTSLSIRT2MAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936607-B2 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNOBECK A/S (DK) | 2005-08-30 | — | — | US | disclosed |