Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.66 |
| ▸ | CTSL | P07711 | 2/20 | 0.66 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.63 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098127 | 0.83 | CTSV (0.65) | CTSVCTSLSIRT2PTK6BCHE | |
| SCHEMBL6352321 | 0.83 | CTSV (0.66) | CTSVCTSLSIRT2PTK6BCHE | |
| SCHEMBL27438028 | 0.83 | CTSV (0.66) | CTSVCTSLSIRT2PTK6BCHE | |
| SCHEMBL6355348 | 0.82 | CTSV (0.58) | CTSVCTSLSIRT2PTK6BCHE | |
| SCHEMBL6359813 | 0.81 | CTSV (0.56) | CTSVCTSLSIRT2PTK6BCHE | |
| SCHEMBL10983488 | 0.80 | CTSV (1.00) | CTSVCTSLSIRT2MEN1ALDH1A1 | |
| SCHEMBL27438490 | 0.80 | CTSV (0.62) | CTSVCTSLSIRT2PTK6BCHE | |
| SCHEMBL27429074 | 0.80 | CTSV (0.65) | CTSVCTSLSIRT2PTK6BCHE | |
| SCHEMBL11920270 | 0.79 | BCHE (0.58) | CTSVCTSLSIRT2BCHEMEN1 | |
| SCHEMBL7835152 | 0.78 | CTSV (0.81) | CTSVCTSLSIRT2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936607-B2 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNOBECK A/S (DK) | 2005-08-30 | — | — | US | disclosed |